Abstract: Abstract EU regional policies have essentially influenced regional development across Europe. These policies and the implementation of programs also have impacted research and have led to several development strands supporting regional change. Diverse concepts, like learning regions, creative milieus, network approaches, transdisciplinary case studies are targeting socio-economic and environmental adaptation. These approaches are focusing on informal cooperation and interaction, voluntary participation of stakeholders and the wider public, best practice applications etc., but are not tackling question of regional identities and values, and are using more casual methodologies in terms of structured learning and knowledge transfer. Therefore, our concept tries to initiate change on the basis of a common set of values and beliefs, which is directing the endogenous, self-organizing and self-sustaining development measures/actions to achieve value-led results. The introduction of two social theory approaches, adapted from Neuro-Linguistic-Programming (NLP), namely the concept of logical levels and the concept of regional modeling will result in a value-led and participatory regional development. On the one hand, logical levels will be used as natural hierarchies in communication, learning, project development and transfer processes, but are also necessary to integrate social, economic, ecological and institutional sustainability along these levels, resulting in value-led logics of sustainability. On the other hand, the application of the modeling concept in connection with logical levels will bring about a structured and appropriate transfer, and implementation of best practice examples from model regions, mainly by focusing on the compatibility of transferred ideas, innovations, imitations with the environmental, social and economic value system of the modeling region.